Winston-Salem is a city in and the county seat of Forsyth County, North Carolina, United States. In the 2020 census, the population was 249,545, making it the second-largest municipality in the Piedmont Triad region, the fifth-most populous city in North Carolina, the third-largest urban area in North Carolina, and the 90th-most populous city in the United States. With a metropolitan population of 675,966, it is the fourth-largest metropolitan area in North Carolina. Winston-Salem is home to the tallest office building in the region, 100 North Main Street, formerly known as the Wachovia Building and now known locally as the Wells Fargo Center.

This description uses material from the Wikipedia article on Winston-Salem, North Carolina and is licensed under the Creative Commons Attribution-ShareAlike License (view authors).